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LEGO: a novel method for gene set over-representation analysis by incorporating network-based gene weights
Pathway or gene set over-representation analysis (ORA) has become a routine task in functional genomics studies. However, currently widely used ORA tools employ statistical methods such as Fisher’s exact test that reduce a pathway into a list of genes, ignoring the constitutive functional non-equiva...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707541/ https://ncbi.nlm.nih.gov/pubmed/26750448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18871 |
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