An Intracellular Arrangement of Histoplasma capsulatum Yeast-Aggregates Generates Nuclear Damage to the Cultured Murine Alveolar Macrophages

Histoplasma capsulatum is responsible for a human systemic mycosis that primarily affects lung tissue. Macrophages are the major effector cells in humans that respond to the fungus, and the development of respiratory disease depends on the ability of Histoplasma yeast cells to survive and replicate...

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Publicado en:Front Microbiol
Autores principales: Pitangui, Nayla de Souza, Sardi, Janaina de Cássia Orlandi, Voltan, Aline R., dos Santos, Claudia T., da Silva, Julhiany de Fátima, da Silva, Rosangela A. M., Souza, Felipe O., Soares, Christiane P., Rodríguez-Arellanes, Gabriela, Taylor, Maria Lucia, Mendes-Giannini, Maria J. S., Fusco-Almeida, Ana M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707385/
https://ncbi.nlm.nih.gov/pubmed/26793172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.01526
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