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The Need for Biomarkers in Diagnosis and Prognosis of Drug-Induced Liver Disease: Does Metabolomics Have Any Role?

Drug-induced liver injury (DILI) is a potentially fatal adverse event and the leading cause of acute liver failure in the US and in the majority of Europe. The liver can be affected directly, in a dose-dependent manner, or idiosyncratically, independently of the dose, and therefore unpredictably. Cu...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Iruzubieta, Paula, Arias-Loste, Maria Teresa, Barbier-Torres, Lucía, Martinez-Chantar, Maria Luz, Crespo, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707380/
https://ncbi.nlm.nih.gov/pubmed/26824035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/386186
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