Modulation of Hydrogen Peroxide-Induced Oxidative Stress in Human Neuronal Cells by Thymoquinone-Rich Fraction and Thymoquinone via Transcriptomic Regulation of Antioxidant and Apoptotic Signaling Genes

Nigella sativa Linn. (N. sativa) and its bioactive constituent Thymoquinone (TQ) have demonstrated numerous pharmacological attributes. In the present study, the neuroprotective properties of Thymoquinone-rich fraction (TQRF) and TQ against hydrogen peroxide- (H(2)O(2)-) induced neurotoxicity in dif...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Ismail, Norsharina, Ismail, Maznah, Azmi, Nur Hanisah, Abu Bakar, Muhammad Firdaus, Basri, Hamidon, Abdullah, Maizaton Atmadini
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707358/
https://ncbi.nlm.nih.gov/pubmed/26823946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2528935
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