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ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway

Tumor cell invasion through the extracellular matrix is accompanied by the formation of invadopodia, which are actin-rich protrusions at the adherent surface of cells at sites of extracellular matrix degradation. Using the invasive human melanoma cell line LOX as a model system, we demonstrate that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tague, Sarah E., Muralidharan, Vandhana, D'Souza-Schorey, Crislyn
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC470733/
https://ncbi.nlm.nih.gov/pubmed/15210957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403531101
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