Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse

The functional and molecular similarities and distinctions between human and murine astrocytes are poorly understood. Here we report the development of an immunopanning method to acutely purify astrocytes from fetal, juvenile, and adult human brains, and to maintain these cells in serum-free culture...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Zhang, Ye, Sloan, Steven A., Clarke, Laura E., Caneda, Christine, Plaza, Colton A., Blumenthal, Paul D., Vogel, Hannes, Steinberg, Gary K., Edwards, Michael S. B., Li, Gordon, Duncan, John A., Cheshier, Samuel H., Shuer, Lawrence M., Chang, Edward F., Grant, Gerald A., Hayden Gephart, Melanie G., Barres, Ben A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707064/
https://ncbi.nlm.nih.gov/pubmed/26687838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.013
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