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Inhibition of Nitric Oxide Synthase Exacerbates Group B Streptococcus Sepsis and Arthritis in Mice

The role of nitric oxide in group B Streptococcus (GBS) infection was evaluated by inhibiting its production with aminoguanidine (AG). AG-treated mice displayed higher mortality rates and more frequent and severe arthritis than controls. Worsening of arthritis correlated with a higher number of GBS...

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Библиографические подробности
Главные авторы: Puliti, Manuela, von Hunolstein, Christina, Bistoni, Francesco, Orefici, Graziella, Tissi, Luciana
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC470700/
https://ncbi.nlm.nih.gov/pubmed/15271956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4891-4894.2004
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