Expression of the LspA1 and LspA2 Proteins by Haemophilus ducreyi Is Required for Virulence in Human Volunteers

Haemophilus ducreyi colocalizes with polymorphonuclear leukocytes and macrophages and evades phagocytosis during experimental infection of human volunteers. H. ducreyi contains two genes, lspA1 and lspA2, which encode predicted proteins of 456 and 543 kDa, respectively. Compared to its wild-type par...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Janowicz, Diane M., Fortney, Kate R., Katz, Barry P., Latimer, Jo L., Deng, Kaiping, Hansen, Eric J., Spinola, Stanley M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470669/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15271912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.8.4528-4533.2004
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