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A method for psychosocial stress-induced reinstatement of cocaine seeking in rats
We describe a novel preclinical model of stress-induced relapse to cocaine use in rats using social defeat stress, an ethologically-valid psychosocial stressor in rodents that closely resembles stressors that promote craving and relapse in humans. Rats self-administered cocaine for 20 days. On days...
שמור ב:
| הוצא לאור ב: | Biol Psychiatry |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706515/ https://ncbi.nlm.nih.gov/pubmed/26257242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.07.002 |
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