Sources of polycyclic aromatic hydrocarbons are associated with gene-specific promoter methylation in women with breast cancer

BACKGROUND: Tobacco smoke, diet and indoor/outdoor air pollution, all major sources of polycyclic aromatic hydrocarbons (PAHs), have been associated with breast cancer. Aberrant methylation may be an early event in carcinogenesis, but whether PAHs influence the epigenome is unclear, particularly in...

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Detalhes bibliográficos
Publicado no:Environ Res
Main Authors: White, Alexandra J., Chen, Jia, Teitelbaum, Susan L., McCullough, Lauren E., Xu, Xinran, Cho, Yoon Hee, Conway, Kathleen, Beyea, Jan, Stellman, Steven D., Steck, Susan E., Mordukhovich, Irina, Eng, Sybil M., Terry, Mary Beth, Engel, Lawrence S., Hatch, Maureen, Neugut, Alfred I., Hibshoosh, Hanina, Santella, Regina M., Gammon, Marilie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706465/
https://ncbi.nlm.nih.gov/pubmed/26671626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envres.2015.11.033
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