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Gamma Interferon Production, but Not Perforin-Mediated Cytolytic Activity, of T Cells Is Required for Prevention of Toxoplasmic Encephalitis in BALB/c Mice Genetically Resistant to the Disease

We previously showed the requirement of both T cells and gamma interferon (IFN-γ)-producing non-T cells for the genetic resistance of BALB/c mice to the development of toxoplasmic encephalitis (TE). In order to define the role of IFN-γ production and the perforin-mediated cytotoxicity of T cells in...

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Autors principals: Wang, Xisheng, Kang, Hoil, Kikuchi, Takane, Suzuki, Yasuhiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC470633/
https://ncbi.nlm.nih.gov/pubmed/15271900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4432-4438.2004
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