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Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence

During oocyte maturation, fertilization, and early embryo development until zygotic genome activation (ZGA), transcription is suppressed, and gene expression is dependent upon the timely activation of stored mRNAs. Embryonic poly(A)-binding protein (EPAB) is the predominant poly(A)-binding protein i...

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Publicado en:Biol Reprod
Autores principales: Lowther, Katie M., Mehlmann, Lisa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706298/
https://ncbi.nlm.nih.gov/pubmed/26134869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.131359
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