Population Pharmacokinetics of Paritaprevir, Ombitasvir, Dasabuvir, Ritonavir, and Ribavirin in Patients with Hepatitis C Virus Genotype 1 Infection: Combined Analysis from 9 Phase 1b/2 Studies

Direct-acting antiviral agents (DAAs) are established as the standard of care for chronic hepatitis C virus (HCV) infection. One of the newest additions to the HCV arsenal is an oral three-DAA combination therapy (i.e., the 3D regimen) that does not require concomitant use of pegylated interferon. T...

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Veröffentlicht in:AAPS J
Hauptverfasser: Mensing, Sven, Polepally, Akshanth R., König, Denise, Khatri, Amit, Liu, Wei, Podsadecki, Thomas J., Awni, Walid M., Menon, Rajeev M., Dutta, Sandeep
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706288/
https://ncbi.nlm.nih.gov/pubmed/26597291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9846-1
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