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The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
A super-saturated self-nanoemulsifying drug delivery system (super-SNEDDS), containing the poorly water-soluble drug halofantrine (Hf) at 150% of equilibrium solubility (S (eq)), was compared in vitro and in vivo with a conventional SNEDDS (75% of S (eq)) with respect to bioavailability and digestib...
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| Publicado no: | AAPS J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706280/ https://ncbi.nlm.nih.gov/pubmed/26486790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9832-7 |
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