The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

A super-saturated self-nanoemulsifying drug delivery system (super-SNEDDS), containing the poorly water-soluble drug halofantrine (Hf) at 150% of equilibrium solubility (S (eq)), was compared in vitro and in vivo with a conventional SNEDDS (75% of S (eq)) with respect to bioavailability and digestib...

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Detaylı Bibliyografya
Yayımlandı:AAPS J
Asıl Yazarlar: Michaelsen, Maria Høtoft, Wasan, Kishor M., Sivak, Olena, Müllertz, Anette, Rades, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706280/
https://ncbi.nlm.nih.gov/pubmed/26486790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9832-7
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