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Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo
Neuroinflammation, immune reactivity and mitochondrial abnormalities are considered as causes and/or contributors to neuronal degeneration. Peroxisome proliferator-activated receptors (PPARs) regulate both inflammatory and multiple other pathways that are implicated in neurodegeneration. In the pres...
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Publicado no: | Hum Mol Genet |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706116/ https://ncbi.nlm.nih.gov/pubmed/26604138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv477 |
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