Systematic identification and annotation of human methylation marks based on bisulfite sequencing methylomes reveals distinct roles of cell type-specific hypomethylation in the regulation of cell identity genes

DNA methylation is a key epigenetic mark that is critical for gene regulation in multicellular eukaryotes. Although various human cell types may have the same genome, these cells have different methylomes. The systematic identification and characterization of methylation marks across cell types are...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Liu, Hongbo, Liu, Xiaojuan, Zhang, Shumei, Lv, Jie, Li, Song, Shang, Shipeng, Jia, Shanshan, Wei, Yanjun, Wang, Fang, Su, Jianzhong, Wu, Qiong, Zhang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705665/
https://ncbi.nlm.nih.gov/pubmed/26635396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1332
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