Randomized phase 2 study of obinutuzumab monotherapy in symptomatic, previously untreated chronic lymphocytic leukemia

Obinutuzumab is a glycoengineered, type 2 anti-CD20 humanized antibody with single-agent activity in relapsed chronic lymphocytic leukemia (CLL). With other CD20 antibodies, a dose-response relationship has been shown. We therefore performed a randomized phase 2 study in symptomatic, untreated CLL p...

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Udgivet i:Blood
Main Authors: Byrd, John C., Flynn, Joseph M., Kipps, Thomas J., Boxer, Michael, Kolibaba, Kathryn S., Carlile, David J., Fingerle-Rowson, Guenter, Tyson, Nicola, Hirata, Jamie, Sharman, Jeff P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Clinical Trials and Observations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705612/
https://ncbi.nlm.nih.gov/pubmed/26472752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-634394
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