A high-density SNP panel reveals extensive diversity, frequent recombination and multiple recombination hotspots within the chicken major histocompatibility complex B region between BG2 and CD1A1

BACKGROUND: The major histocompatibility complex (MHC) is present within the genomes of all jawed vertebrates. MHC genes are especially important in regulating immune responses, but even after over 80 years of research on the MHC, much remains to be learned about how it influences adaptive and innat...

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Bibliografski detalji
Izdano u:Genet Sel Evol
Glavni autori: Fulton, Janet E., McCarron, Amy M., Lund, Ashlee R., Pinegar, Kara N., Wolc, Anna, Chazara, Olympe, Bed’Hom, Bertrand, Berres, Mark, Miller, Marcia M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705597/
https://ncbi.nlm.nih.gov/pubmed/26743767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-015-0181-x
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