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The Costimulatory Molecule ICOS Regulates Host Th1 and Follicular Th Cell Differentiation in Response to Plasmodium chabaudi chabaudi AS Infection

Blood-stage Plasmodium chabaudi chabaudi AS infection requires cell- and Ab-mediated immunity to control acute and persistent infection, respectively. ICOS regulates CD4(+) T cell activation and promotes the induction of follicular Th (T(FH)) cells, CD4(+) T cells that support B cell affinity matura...

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Vydáno v:J Immunol
Hlavní autoři: Wikenheiser, Daniel J., Ghosh, Debopam, Kennedy, Brian, Stumhofer, Jason S.
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705592/
https://ncbi.nlm.nih.gov/pubmed/26667167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403206
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