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Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes

Human pluripotent stem cell-derived cardiomyocytes (CMs) are a promising tool for cardiac cell therapy. Although transplantation of induced pluripotent stem cell (iPSC)-derived CMs have been reported in several animal models, the treatment effect was limited, probably due to poor optimization of the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Funakoshi, Shunsuke, Miki, Kenji, Takaki, Tadashi, Okubo, Chikako, Hatani, Takeshi, Chonabayashi, Kazuhisa, Nishikawa, Misato, Takei, Ikue, Oishi, Akiko, Narita, Megumi, Hoshijima, Masahiko, Kimura, Takeshi, Yamanaka, Shinya, Yoshida, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705488/
https://ncbi.nlm.nih.gov/pubmed/26743035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19111
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