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Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import

To translate the 13 mtDNA-encoded mRNAs involved in oxidative phosphorylation (OXPHOS), mammalian mitochondria contain a dedicated set of ribosomes comprising rRNAs encoded by the mitochondrial genome and mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and imported into the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nouws, Jessica, Goswami, Arvind V., Bestwick, Megan, McCann, Beverly Jo, Surovtseva, Yulia V., Shadel, Gerald S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705416/
https://ncbi.nlm.nih.gov/pubmed/26586915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689299
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