Mutations in Replicative Stress Response Pathways Are Associated with S Phase-specific Defects in Nucleotide Excision Repair

Nucleotide excision repair (NER) is a highly conserved pathway that removes helix-distorting DNA lesions induced by a plethora of mutagens, including UV light. Our laboratory previously demonstrated that human cells deficient in either ATM and Rad3-related (ATR) kinase or translesion DNA polymerase...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bélanger, François, Angers, Jean-Philippe, Fortier, Émile, Hammond-Martel, Ian, Costantino, Santiago, Drobetsky, Elliot, Wurtele, Hugo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705374/
https://ncbi.nlm.nih.gov/pubmed/26578521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.685883
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