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4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry

Novel psychoactive substances are continuously developed to circumvent legislative and regulatory efforts. A new synthetic cathinone, 4-methoxy-α-PVP, was identified for the first time in illegal products; however, the metabolism of this compound is not known. Complete metabolic profiles are needed...

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Detalhes bibliográficos
Publicado no:Forensic Toxicol
Main Authors: Ellefsen, Kayla N., Wohlfarth, Ariane, Swortwood, Madeleine J., Diao, Xingxing, Concheiro, Marta, Huestis, Marilyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705136/
https://ncbi.nlm.nih.gov/pubmed/26793277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11419-015-0287-4
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