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The yeast prion [SWI(+)] abolishes multicellular growth by triggering conformational changes of multiple regulators required for flocculin gene expression
While transcription factors are prevalent among yeast prion proteins, the role of prion-mediated transcriptional regulation remains elusive. We show here that the yeast prion [SWI(+)] abolishes flocculin (FLO) gene expression and results in a complete loss of multicellularity. Further investigation...
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| Publicado en: | Cell Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704862/ https://ncbi.nlm.nih.gov/pubmed/26711350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.060 |
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