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Disruption of Methionine Metabolism in Drosophila melanogaster Impacts Histone Methylation and Results in Loss of Viability

Histone methylation levels, which are determined by the action of both histone demethylases and methyltransferases, impact multiple biological processes by affecting gene expression activity. Methionine metabolism generates the major methyl donor S-adenosylmethionine (SAM) for histone methylation. T...

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Publicat a:G3 (Bethesda)
Autors principals: Liu, Mengying, Barnes, Valerie L., Pile, Lori A.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704710/
https://ncbi.nlm.nih.gov/pubmed/26546310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.024273
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