Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult

BACKGROUND: During osteoarthritis and following surgical procedures, the environment of the knee is rich in proinflammatory cytokines such as IL-1. Introduction of tissue-engineered cartilage constructs to a chemically harsh milieu may limit the functionality of the implanted tissue over long period...

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Publicado en:Arthritis Res Ther
Autores principales: Tan, Andrea R., VandenBerg, Curtis D., Attur, Mukundan, Abramson, Steven B., Knight, Martin M, Bulinski, J. Chloe, Ateshian, Gerard A., Cook, James L, Hung, Clark T.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704536/
https://ncbi.nlm.nih.gov/pubmed/26667364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0876-y
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