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Aberrant regulation of synchronous network activity by the attention‐deficit/hyperactivity disorder‐associated human dopamine D4 receptor variant D4.7 in the prefrontal cortex
The hD4.7 variant has been linked to attention‐deficit/hyperactivity disorder (ADHD); however, the underlying mechanism is unknown. We found that activation of hD4.7 induced over‐suppression of glutamatergic excitatory network bursts and under‐suppression of GABAergic inhibitory network bursts in th...
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| Publicado no: | J Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704499/ https://ncbi.nlm.nih.gov/pubmed/26541360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271317 |
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