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Aberrant regulation of synchronous network activity by the attention‐deficit/hyperactivity disorder‐associated human dopamine D4 receptor variant D4.7 in the prefrontal cortex

The hD4.7 variant has been linked to attention‐deficit/hyperactivity disorder (ADHD); however, the underlying mechanism is unknown. We found that activation of hD4.7 induced over‐suppression of glutamatergic excitatory network bursts and under‐suppression of GABAergic inhibitory network bursts in th...

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Detaylı Bibliyografya
Yayımlandı:J Physiol
Asıl Yazarlar: Zhong, Ping, Liu, Wenhua, Yan, Zhen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704499/
https://ncbi.nlm.nih.gov/pubmed/26541360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271317
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