Differences in the efficacy of S-1 monotherapy according to histological type in pretreated patients with advanced non-small cell lung cancer

BACKGROUND: S-1 is a novel antimetabolic agent that inhibits thymidylate synthase. The expression of thymidylate synthase is higher in squamous (Sq) non-small cell lung cancer (NSCLC) than in non-Sq NSCLC. The aim of this retrospective study was to assess the efficacy of S-1 monotherapy for advanced...

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Detalhes bibliográficos
Publicado no:Thorac Cancer
Main Authors: Hisamatsu, Yasushi, Murakami, Haruyasu, Akamatsu, Hiroaki, Kimura, Madoka, Mori, Keita, Imai, Hisao, Ono, Akira, Shukuya, Takehito, Taira, Tetsuhiko, Kenmotsu, Hirotsugu, Naito, Tateaki, Endo, Masahiro, Nakajima, Takashi, Takahashi, Toshiaki, Yamamoto, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704320/
https://ncbi.nlm.nih.gov/pubmed/26766988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12071
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