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Detection of c-kit mutational status in small-cell lung cancer in a Chinese cohort
BACKGROUND: Overexpression of KIT (CD117), a tyrosine kinase receptor, and its natural ligand, stem cell factor, are found in small-cell lung cancer (SCLC). Somatic mutations of the proto-oncogene c-kit constitutively activate KIT expression in a ligand-independent way. To explore the clinical value...
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| Publicado no: | Thorac Cancer |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704306/ https://ncbi.nlm.nih.gov/pubmed/26767005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12082 |
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