Novobiocin Inhibits the Antimicrobial Resistance Acquired through DNA Damage-Induced Mutagenesis in Acinetobacter baumannii

Acinetobacter baumannii, a worldwide emerging nosocomial pathogen, acquires antimicrobial resistances in response to DNA-damaging agents, which increase the expression of multiple error-prone DNA polymerase components. Here we show that the aminocoumarin novobiocin, which inhibits the DNA damage res...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Jara, Luis M., Pérez-Varela, María, Corral, Jordi, Arch, Marta, Cortés, Pilar, Bou, Germán, Aranda, Jesús, Barbé, Jordi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704144/
https://ncbi.nlm.nih.gov/pubmed/26503651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01810-15
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