Novobiocin Inhibits the Antimicrobial Resistance Acquired through DNA Damage-Induced Mutagenesis in Acinetobacter baumannii

Acinetobacter baumannii, a worldwide emerging nosocomial pathogen, acquires antimicrobial resistances in response to DNA-damaging agents, which increase the expression of multiple error-prone DNA polymerase components. Here we show that the aminocoumarin novobiocin, which inhibits the DNA damage res...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Jara, Luis M., Pérez-Varela, María, Corral, Jordi, Arch, Marta, Cortés, Pilar, Bou, Germán, Aranda, Jesús, Barbé, Jordi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704144/
https://ncbi.nlm.nih.gov/pubmed/26503651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01810-15
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