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Autophosphorylation at Thr279 of Entamoeba histolytica atypical kinase EhAK1 is required for activity and regulation of erythrophagocytosis

Phagocytosis plays a key role in survival and pathogenicity of Entamoeba histolytica. We have recently demonstrated that an atypical kinase EhAK1 is involved in phagocytosis in this parasite. It is recruited to the phagocytic cups through interaction with EhCaBP1. EhAK1 manipulates actin dynamics by...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mansuri, M Shahid, Babuta, Mrigya, Ali, Mohammad Sabir, Bharadwaj, Ravi, jhingan, Gagan Deep, Gourinath, Samudrala, Bhattacharya, Sudha, Bhattacharya, Alok
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703981/
https://ncbi.nlm.nih.gov/pubmed/26739245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16969
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