Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriage

Increased nasopharyngeal colonization density has been associated with pneumonia. We used experimental human pneumococcal carriage to investigate whether upper respiratory tract viral infection predisposes individuals to carriage. A total of 101 healthy subjects were screened for respiratory virus b...

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Udgivet i:Mucosal Immunol
Main Authors: Glennie, S, Gritzfeld, J F, Pennington, S H, Garner-Jones, M, Coombes, N, Hopkins, M J, Vadesilho, C F, Miyaji, E N, Wang, D, Wright, A D, Collins, A M, Gordon, S B, Ferreira, D M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703943/
https://ncbi.nlm.nih.gov/pubmed/25921341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.35
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