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Diazepam dependence prevented by glutamate antagonists.

Long-term treatment leads to tolerance to and dependence on benzodiazepines. Abrupt termination of benzodiazepine administration triggers the expression of signs of dependence. Mice withdrawn from chronic treatment with diazepam showed a time-related evolution of anxiety, muscle rigidity, and seizur...

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Detalhes bibliográficos
Main Authors: Steppuhn, K G, Turski, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47038/
https://ncbi.nlm.nih.gov/pubmed/8341715
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