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Muscle A-Kinase Anchoring Protein-α is an Injury-Specific Signaling Scaffold Required for Neurotrophic- and Cyclic Adenosine Monophosphate-Mediated Survival

Neurotrophic factor and cAMP-dependent signaling promote the survival and neurite outgrowth of retinal ganglion cells (RGCs) after injury. However, the mechanisms conferring neuroprotection and neuroregeneration downstream to these signals are unclear. We now reveal that the scaffold protein muscle...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wang, Yan, Cameron, Evan G., Li, Jinliang, Stiles, Travis L., Kritzer, Michael D., Lodhavia, Rahul, Hertz, Jonathan, Nguyen, Tu, Kapiloff, Michael S., Goldberg, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703706/
https://ncbi.nlm.nih.gov/pubmed/26844267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.10.025
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