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Determination of pK(a) and Hydration Constants for a Series of α-Keto-Carboxylic Acids Using Nuclear Magnetic Resonance Spectrometry
The determination of the acid-base dissociation constants, and thus the pK(a) values, of α-keto acids such as pyruvic acid is complex due to the existence of these acids in their hydrated and non-hydrated or oxo-state. Equilibria involved in the hydration and dehydration of the α-keto group of pyruv...
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| Foilsithe in: | J Pharm Sci |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703567/ https://ncbi.nlm.nih.gov/pubmed/26149194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24539 |
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