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NDRG2 Expression Decreases Tumor-Induced Osteoclast Differentiation by Down-regulating ICAM1 in Breast Cancer Cells

Bone matrix is properly maintained by osteoclasts and osteoblasts. In the tumor microenvironment, osteoclasts are increasingly differentiated by the various ligands and cytokines secreted from the metastasized cancer cells at the bone metastasis niche. The activated osteoclasts generate osteolytic l...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Kim, Bomi, Nam, Sorim, Lim, Ji Hyun, Lim, Jong-Seok
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703347/
https://ncbi.nlm.nih.gov/pubmed/26759696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.105
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