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Biolayer Interferometry: A Novel Method to Elucidate Protein–Protein and Protein–DNA Interactions in the Mitochondrial DNA Replisome

A lack of effective treatment for mitochondrial diseases prompts scientists to investigate the molecular processes that underlie their development. The major cause of mitochondrial diseases is dysfunction of the sole mitochondrial DNA polymerase, DNA polymerase γ (Pol γ). The development of treatmen...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Ciesielski, Grzegorz L., Hytönen, Vesa P., Kaguni, Laurie S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703100/
https://ncbi.nlm.nih.gov/pubmed/26530686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3040-1_17
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