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Vilya, a component of the recombination nodule, is required for meiotic double-strand break formation in Drosophila

Meiotic recombination begins with the induction of programmed double-strand breaks (DSBs). In most organisms only a fraction of DSBs become crossovers. Here we report a novel meiotic gene, vilya, which encodes a protein with homology to Zip3-like proteins shown to determine DSB fate in other organis...

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Publicat a:eLife
Autors principals: Lake, Cathleen M, Nielsen, Rachel J, Guo, Fengli, Unruh, Jay R, Slaughter, Brian D, Hawley, R Scott
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703084/
https://ncbi.nlm.nih.gov/pubmed/26452093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08287
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