Rapid increases in immature synapses parallel estrogen-induced hippocampal learning enhancements

Dramatic increases in hippocampal spine synapse density are known to occur within minutes of estrogen exposure. Until now, it has been assumed that enhanced spinogenesis increased excitatory input received by the CA1 pyramidal neurons, but how this facilitated learning and memory was unclear. Delive...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Phan, Anna, Suschkov, Sarah, Molinaro, Luke, Reynolds, Kathryn, Lymer, Jennifer M., Bailey, Craig D. C., Kow, Lee-Ming, MacLusky, Neil J., Pfaff, Donald W., Choleris, Elena
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703013/
https://ncbi.nlm.nih.gov/pubmed/26655342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522150112
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