A Cell-Free Assembly System for Generating Infectious Human Papillomavirus 16 Capsids Implicates a Size Discrimination Mechanism for Preferential Viral Genome Packaging

We have established a cell-free in vitro system to study human papillomavirus type 16 (HPV16) assembly, a poorly understood process. L1/L2 capsomers, obtained from the disassembly of virus-like particles (VLPs), were incubated with nuclear extracts to provide access to the range of cellular proteins...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Cerqueira, Carla, Pang, Yuk-Ying S., Day, Patricia M., Thompson, Cynthia D., Buck, Christopher B., Lowy, Douglas R., Schiller, John T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702664/
https://ncbi.nlm.nih.gov/pubmed/26559838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02497-15
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