Targeting Swine Leukocyte Antigen Class I Molecules for Proteasomal Degradation by the nsp1α Replicase Protein of the Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Strain JXwn06

Porcine reproductive and respiratory syndrome virus (PRRSV) is a critical pathogen of swine, and infections by this virus often result in delayed, low-level induction of cytotoxic T lymphocyte (CTL) responses in pigs. Here, we report that a Chinese highly pathogenic PRRSV strain possessed the abilit...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Du, Jige, Ge, Xinna, Liu, Ying, Jiang, Ping, Wang, Zhe, Zhang, Ruimin, Zhou, Lei, Guo, Xin, Han, Jun, Yang, Hanchun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702659/
https://ncbi.nlm.nih.gov/pubmed/26491168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02307-15
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