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Tissue Plasminogen Activator Coating on Implant Surfaces Reduces Staphylococcus aureus Biofilm Formation

Staphylococcus aureus biofilm infections of indwelling medical devices are a major medical challenge because of their high prevalence and antibiotic resistance. As fibrin plays an important role in S. aureus biofilm formation, we hypothesize that coating of the implant surface with fibrinolytic agen...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Kwiecinski, Jakub, Na, Manli, Jarneborn, Anders, Jacobsson, Gunnar, Peetermans, Marijke, Verhamme, Peter, Jin, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702636/
https://ncbi.nlm.nih.gov/pubmed/26519394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02803-15
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