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Dynein Light Chain LC8 Is Required for RNA Polymerase I-Mediated Transcription in Trypanosoma brucei, Facilitating Assembly and Promoter Binding of Class I Transcription Factor A

Dynein light chain LC8 is highly conserved among eukaryotes and has both dynein-dependent and dynein-independent functions. Interestingly, LC8 was identified as a subunit of the class I transcription factor A (CITFA), which is essential for transcription by RNA polymerase I (Pol I) in the parasite T...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Kirkham, Justin K., Park, Sung Hee, Nguyen, Tu N., Lee, Ju Huck, Günzl, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702606/
https://ncbi.nlm.nih.gov/pubmed/26459761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00705-15
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