pH-Dependent Formation and Disintegration of the Influenza A Virus Protein Scaffold To Provide Tension for Membrane Fusion

Influenza virus is taken up from a pH-neutral extracellular milieu into an endosome, whose contents then acidify, causing changes in the viral matrix protein (M1) that coats the inner monolayer of the viral lipid envelope. At a pH of ∼6, M1 interacts with the viral ribonucleoprotein (RNP) in a putat...

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Vydáno v:J Virol
Hlavní autoři: Batishchev, O. V., Shilova, L. A., Kachala, M. V., Tashkin, V. Y., Sokolov, V. S., Fedorova, N. V., Baratova, L. A., Knyazev, D. G., Zimmerberg, J., Chizmadzhev, Y. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702562/
https://ncbi.nlm.nih.gov/pubmed/26468548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01539-15
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