Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development

BACKGROUND: Adenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in mesenchymal cells. However, the roles of Apc in regula...

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Vydáno v:BMC Biol
Hlavní autoři: Luo, Yongfeng, El Agha, Elie, Turcatel, Gianluca, Chen, Hui, Chiu, Joanne, Warburton, David, Bellusci, Saverio, Qian, Bang-Ping, Menke, Douglas B., Shi, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702410/
https://ncbi.nlm.nih.gov/pubmed/26092405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0153-1
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