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Overexpression of SIRT6 in the hippocampal CA1 impairs the formation of long-term contextual fear memory
Histone modifications have been implicated in learning and memory. Our previous transcriptome data showed that expression of sirtuins 6 (SIRT6), a member of Histone deacetylases (HDACs) family in the hippocampal cornu ammonis 1 (CA1) was decreased after contextual fear conditioning. However, the rol...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702175/ https://ncbi.nlm.nih.gov/pubmed/26732053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18982 |
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