Lack of netrin-4 modulates pathologic neovascularization in the eye

Netrins are a family of matrix-binding proteins that function as guidance signals. Netrin-4 displays pathologic roles in tumorigenesis and neovascularization. To answer the question whether netrin-4 acts either pro- or anti-angiogenic, angiogenesis in the retina was assessed in Ntn-4(−/−) mice with...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kociok, Norbert, Crespo-Garcia, Sergio, Liang, Yong, Klein, Sabrina V., Nürnberg, Christina, Reichhart, Nadine, Skosyrski, Sergej, Moritz, Eva, Maier, Anna-Karina, Brunken, William J., Strauß, Olaf, Koch, Manuel, Joussen, Antonia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702134/
https://ncbi.nlm.nih.gov/pubmed/26732856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18828
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