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NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity

Nucleolar and spindle-associated protein (NuSAP) is a microtubule-associated protein that functions as a microtubule stabiliser. Depletion of NuSAP leads to severe mitotic defects, however the mechanism by which NuSAP regulates mitosis remains elusive. In this study, we identify the microtubule depo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Chenyu, Zhang, Yajun, Yang, Qiaoyun, Ye, Fan, Sun, Stella Ying, Chen, Ee Sin, Liou, Yih-Cherng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702128/
https://ncbi.nlm.nih.gov/pubmed/26733216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18773
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