Molecular docking analysis of known flavonoids as duel COX-2 inhibitors in the context of cancer

Cyclooxygenase-2 (COX-2) catalyzed synthesis of prostaglandin E2 and it associates with tumor growth, infiltration, and metastasis in preclinical experiments. Known inhibitors against COX-2 exhibit toxicity. Therefore, it is of interest to screen natural compounds like flavanoids against COX-2. Mole...

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Detalhes bibliográficos
Publicado no:Bioinformation
Main Authors: Dash, Raju, Uddin, Mir Muhammad Nasir, Hosen, S.M. Zahid, Rahim, Zahed Bin, Dinar, Abu Mansur, Kabir, Mohammad Shah Hafez, Sultan, Ramiz Ahmed, Islam, Ashekul, Hossain, Md Kamrul
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2015
Assuntos:
Hypothesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702032/
https://ncbi.nlm.nih.gov/pubmed/26770028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630011543
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