Cocaine Self-Administration Experience Induces Pathological Phasic Accumbens Dopamine Signals and Abnormal Incentive Behaviors in Drug-Abstinent Rats

Chronic exposure to drugs of abuse is linked to long-lasting alterations in the function of limbic system structures, including the nucleus accumbens (NAc). Although cocaine acts via dopaminergic mechanisms within the NAc, less is known about whether phasic dopamine (DA) signaling in the NAc is alte...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Saddoris, Michael P., Wang, Xuefei, Sugam, Jonathan A., Carelli, Regina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701963/
https://ncbi.nlm.nih.gov/pubmed/26740664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3468-15.2016
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